Acetophenone Azine: The 2021 American Contact Dermatitis Society Allergen of the Year

The American Contact Dermatitis Society chose acetophenone azine (AA) as the 2021 Allergen of Year. Acetophenone is an emerging contact allergen that often associated with use sports equipment and footwear. pattern dermatitis initially starts locally at site but can develop into a generalized dermatitis. Strong suspicion necessary to diagnose AA allergy, patch testing should be completed potentially relevant and/or shoes. not yet available commercial patch-test preparation, optimal concentration 0.1% in acetone or petrolatum. This column serves introduction highlights diagnosis, management, for allergy.